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Beta glucan is a naturally occurring compound that is formed from sugar molecules, and found in many plant sources.
There have been a variety of health benefits linked to glucans, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides.
Vital Info
- The body strengthens the immune system in response to beta glucan, increasing the production of white blood cells.
- Glucan molecules may help mobilize the immune system and put cells on 'high alert'.
- Therefore, cells in the immune system can modify your immune system responses.
- Over 200,000 verified studies on β-glucans have been published on PubMed.gov.
The body strengthens the immune system in response to beta glucan and increases the production of white blood cells; as well as, helps to reduce allergic responses to non-harmful molecules.
Glucan molecules can help to mobilize the immune system to protect the body from invaders.
Taking beta 1 3d glucan has been linked to reduced blood cholesterol concentrations. Scientific studies found that regular consumption of glucan molecules is important for regulating blood cholesterol.
Cholesterol levels are an important factor in maintaining a healthy weight; meaning, glucans should be a part of everyone’s diet.
These fibrous molecules help regulate intestinal motility, reducing symptoms of indigestion while decreasing low-density lipoprotein levels. This process will help lower the risk of cardiovascular disease.
Suggested reading: 8 Practical Ways to Improve Your Immune System
Studies on Beta Glucan
Some preliminary studies on animal models show that beta 1 3d glucan will help to reduce or destroy tumors from cancer. (1)
Animals that were administered this amazing molecule showed longer survival times, and humans that took beta glucans in another study also lived longer.
Beta 1 3d glucan has been shown to have a role in helping wounds heal, accelerating the body's recovery from surgery, reducing tissue damage from arthritis, and reducing nasal inflammation due to allergies. (2)
Beta Glucan Medical Uses and Natural Sources
Medical Uses
For over half a century (50 years), medical scientists have been testing β-glucans. The outcome has been over 200,000 verified studies that have been published on PubMed.gov. Over 250 medical studies are underway on ClinicalTrials.gov.
They contain “immunomodulating activity” and increase our “immune defense by activating the complement system, enhancing macrophages and natural killer cell function.” (3)
In layman's terms, this means that glucans can enhance your immune response like no other, and they are used for a wide variety of ailments: (4)
- Allergies
- Asthma
- Bloating
- Common colds
- Flu
- Diabetes
- Ear infections
- Fibromyalgia
- Hepatitis
- High cholesterol
- High blood pressure
- Irritable bowel disease
- Liver problems
- Lyme disease
- Multiple sclerosis
- Physical and emotional stress
- Rheumatoid arthritis
- Ulcerative colitis
Most people have never heard of beta glucans before, yet there are nearly 17,000 peer-reviewed articles discussing them in scientific journals. Actually, it is truly a wonder that this fiber-like molecule has not "hit mainstream” yet as a supplement because the health benefits are absolutely superb.
Belonging to a group of physiologically active compounds called biological response modifiers, beta glucans are naturally occurring sugars that act as highly conserved structural components of cell walls in fungi, seaweed, and yeast. (5)
Heart-healthy fiber is a core aspect of overall health and wellness.
Found in barely, beans, fruits, lentils, oat bran, and peas; fiber slows digestion and has been clinically shown to lower cholesterol. (6)
Glucans have also been found to be very effective at healing skin conditions such as bedsores, dermatitis, diabetic ulcers, eczema, wounds, radiation burns, and even wrinkles.
Fascinatingly, “In contrast to microorganisms, tumor cells, as well as other host cells, lack beta glucan as a surface component.” This may be one reason why cancer is so vulnerable to glucan supplementation. (7)
With that said, few people understand why and how they work. Czech researchers put it best:
“Despite almost 150 years of research, the exact mechanisms of their action remain unclear. (8)
The number and types of glucans seem limitless. In the words of the University of Louisville, Department of Pathology, “The number of individual glucans is almost as great as the number of sources used for their isolation.”
Despite the limited number of naturally occurring sources of beta glucan, there are common food sources rich in glucans and fiber:
- Oats (and oatmeal)
- Whole grains
- Cereals
- Yeasts
- Edible mushrooms (Shiitake, Maitake, Wood cauliflower, and snow mushrooms)
- Celery
- Chi-chian leaves
- Carrot
- Radish
- Seaweed
- Algae
Beta-1, 3D Glucan
Of all the beta glucans that have been studied, Beta-1, 3D Glucan seems to hold the most health potential for individuals who supplement with it.
Over 50 years of research from prestigious universities around the world document its health prowess Beta-1, 3D Glucan has been shown to boost the immune system to provide support and balance.
Medical doctors are even using (1–3)-β-D glucan as a non-invasive way to determine if patients have been affected with fungal infections. (9) It is unlike other immune supplements that simply stimulate or alter the immune response in unnatural ways.
No Known Side Effects
Essentially, the main “side effect” of beta glucan is that it helps your body heal from sickness and disease.
In all seriousness, the majority of clinical trials conducted on animals and humans have not uncovered any adverse effects related to taking beta glucans whatsoever.
For example, a 13-week clinical trial uncovered that when a maximum deliverable oral dose was administered to rats, it was given with no harmful effects measured.
When people take them orally, they are well tolerated and are considered by the FDA to be generally regarded as safe (GRAS rating).
Explore FAQs: Learn more about any side effects associated with glucan
Two Important Side Notes
First and foremost, always be sure to check first with your healthcare provider before taking immune-boosting supplements.
Various sources stress the importance that glucans are so effective at enhancing immune function that they may interfere with immune-suppressing drugs that autoimmune patients regularly take. (10)
If you were thinking of purchasing Beta-1, 3D Glucan for a family member or yourself, make sure the following immunosuppressants are not being taken:
- Azathioprine (Imuran)
- Basiliximab (Simulect)
- Cyclosporine (Neoral, Sandimmune)
- Daclizumab (Zenapax)
- Muromonab-CD3 (OKT3, Orthoclone OKT3)
- Mycophenolate (CellCept)
- Tacrolimus (FK506, Prograf)
- Sirolimus (Rapamune)
- Prednisone (Deltasone, Orasone)
- Corticosteroids (glucocorticoids) and others.
Secondly, not all glucan products on the market are created equal and it is absolutely vital to steer away from synthetic varieties with harmful fillers. An article published in the journal Food and Chemical Toxicology stresses this point:
“In addition, variations in β-glucan structure and composition are highly dependent on the particular method by which a β-glucan preparation is processed or manufactured, and these variations can have a significant impact on their respective immune stimulatory activity and effect that could also lead to significant toxicity when crude preparations are used therapeutically.”
Like any supplement, be sure to purchase beta glucan supplements from a trusted source and under the guidance of your natural health care provider.
Continue reading: All the Info You Need to Boost Your Immune System
FAQ
For more information about beta glucan, Better Way Health and more, visit our FAQ page. To speak to an Amazing Customer Experience Specialist, give us a call at 800.746.7640or email us at hello@betterwayhealth.com
Our Beta Glucan goes through a rigorous purification process developed by the creator: AJ Lanigan. Once this purification process takes place, only about 10% of a given “batch” meets our 85% minimum purity standard. The “scraps”, so to speak (the other 90% of the batches), are then sold off and marketed by other companies. In addition, the product has been tested time and time again to prove its efficacy. When compared to other heavily marketed immune system products, our product comes out on top every single time. These comparison studies are conducted by a disinterested third party researcher at the University of Louisville: Dr. Vaclav Vetvicka. In these studies, immune response levels are safely tested on both humans and animals. Our product is also Non-GMO and encased in a Vegan, plant-based capsule.
-Better Way Health
Better Way Health Beta Glucan is certainly one of the most renowned brands out there in the marketplace. In our world of immune system support, when you ask “What’s the best immune system supplement out there?”; well, the Better Way Health name is the most recognized.
Anyone who has spent time reviewing side-by-side comparisons of our product with, again, just about any other kind of immune compound; regardless of the source, you’re going to find that Beta Glucan 500 by Better Way Health outperforms all competitors. This has been the case for years; this is not a new phenomenon that conclusive research done by disinterested third parties in major universities and teaching hospitals all over the world agree that the potency of Glucan 500 makes it 100% the leading immune system product available.
The immunomodulating aspects of Beta Glucan is what makes it safer and more efficacious than the competition. Studies confirm our Beta Glucan is the most effective immune system product on the market, including even other beta glucans. The patented purification process developed by AJ Lanigan is what makes our Beta Glucan more biologically active and beneficial to consumers.
-Better Way Health
This is rather easy to answer. Our Beta Glucan has one really big advantage in that it is the most studied natural immonomodulator of them all. The biological studies number in the tens of thousands. For most other products, you may find 10 to 15 studies. If you have 10,000+ papers from all around the world, that cannot be ignored.
-Dr. Vaclav Vetvicka
We did a couple of studies and we published them comparing some individual glucans to individual immune-modulators like Echinacea. That is one example, most of the clinical studies on that plant failed because one company is using leaves, one is using roots and each has a different quality inside so you never know what you get.
With the "mixture" type products, it is even worse because some manufacturers are just trying to either increase the price by putting five things together, so it’s not 30 bucks it’s now $50. None of these manufacturers are actually doing any research on the combinations of their ingredients.
-Dr. Vaclav Vetvicka
This topic is like comparing Super Bowl Champions (Better Way Health Beta Glucan) to Recreational Sports Teams (the competition). There is practically no comparison; when you look at the average Immune System Product on the market, even an abundance of it may only be able to raise your Immune Response 2 to 3 percent. That increase, however, may be costing you thousands of dollars; thus, I would not consider that to be much of a comparison. For about 1$ a day, with our Glucan 500 product, you can get your immune response up to about 60% (double the innate human immunity): no one can compete with that efficacy.
-AJ Lanigan
Beta Glucan has been studied for over 50 years at major universities and teaching hospitals, all of which are disinterested third party researchers. There are more than 150,000 glucan studies on PubMed.gov and nearly 50,000 studies involving glucans and humans. Our Beta Glucan specifically has been featured in over 20 medical journals, including the prestigious American Journal of Immunology and the Journal of Medicinal Food.
-Better Way Health
There are more than 150,000 studies on Glucan that you can find on Medline and PubMed. Roughly, you can also find 50,000 studies on Glucans and their interaction with Humans. Throughout these studies, there has never been an adverse side effect found with our Beta Glucan.
-AJ Lanigan
Other than the thousands of studies out there, there is an excellent book by Dr. Vaclav Vetvicka from the University of Louisville entitled, Beta Glucan: Nature’s Secret. It’s about 157 pages and provides a quick, educational read for those interested in everything Beta Glucan: the history, safety, benefits, and mechanism of action of Beta Glucan. The bibliography included in the book provides dozens of other peer-reviewed articles and journals for curious consumers.
-AJ Lanigan
If somebody goes to PubMed.Gov or some kind of scientific database, there is about 150,000 hits now and about 50 new papers appear every week. The research is really booming.
-Dr. Vaclav Vetvicka
Anyone / anything with an immune system can benefit from taking Beta Glucan, including both humans and pets. Our immune system is our first line of defense and it can always use additional “soldiers.” Keep in mind that our Beta Glucan makes a person’s immune system smarter and stronger, but never causes overstimulation or harm. There are no known side effects.
-Better Way Health
“Anyone who is living can benefit from a healthier Immune System” – A.J. Lanigan
People who want proper support for their Immune System should use this product. People who simply want to maintain or regain their good health can benefit from this product as well.
Many conditions, whether environmental or physical, put significant stress on the Immune System.
Infectious Disease, Cardiovascular Disease, Chemotherapy Treatment, Radiation, Allergies, Asthma, and Stress are all severely taxing on the body. This type of suppression and depression of the immune system is what puts everyone’s health person at risk. Be proactive; take a product that benefits your overall health by enhancing your body’s own natural ability to stay well and recuperate.
That’s right, anyone and everyone can benefit from the immune modulating effects of Beta-1, 3D Glucan.
-AJ Lanigan
For people who are under heavy stress or are just working in some kind of extreme conditions, they need all the help they can get. Proactive supplementation is also recommended for Flu and Cold seasons
-Dr. Vaclav Vetvicka
For maximum immune response, take one 500mg capsule per 50 lbs. of body weight. For example, if you weigh around 150 lbs. you would need to take 3 capsules per day. All capsules should be taken first thing in the morning on an empty stomach. After taking your capsules, wait 30 minutes before eating or consuming other products. If you forget to take your capsules in the morning it is safe to go ahead and take your Beta Glucan during the day, although the benefits will not be as significant. Remember, these dosage instructions are for maximum immune response, any dose (i.e., 1 capsule per day) is still extremely beneficial.
-Better Way Health
Maximum dose is based on body weight: Remember, your weight in kg’s is your weight in pounds divided by 2.2. For example, a 220lb person is 100kg. The guideline for maintaining good health is 2mg/kg of body weight per day. For the 220 pound person mentioned above, who is 100kg, they should take 200mg per day and that would be extraordinarily effective Immune Support.
For people who want or need additional immune support, there is a 500mg capsule. The recommendation for this group is 20 mg/kg/day or a 500mg capsule for every 50 pounds of body weight. Thus, a 100kg person (220lb) would take 4 capsules of the 500mg per day; for a 110 pound person, two capsules of the 500mg Beta Glucan would suffice. If your weight does not calculate out to an exact dose, round up or down depending on your needs; or you can average it out by taking 1 capsule one day and 2 the next.
The point is, the product is safe and you can be flexible with dosage if you reflect the guidelines above. Even taking just 1 - 500mg capsule each day is an extremely beneficial dose.
Neutrophils and monocytes in our blood live only for a couple of days. That is why you have a need for constant, daily, glucan consumption because they die and the new cells are appearing and then you need the glucan again to boost these immune cells.
-Dr. Vaclav Vetvicka
No, there are no known side effects pertaining to our Beta Glucan. There have been numerous safe human and animal studies showing the safety of Beta Glucan. The Food and Drug Administration (FDA) has given our Beta Glucan GRAS rating, which means Generally Recognized as Safe under the Food, Drug, and Cosmetic Act. This certification is extremely hard to achieve especially when it comes to a dietary supplement.
-Better Way Health
You can absolutely take this product without worry! There have been multiple studies done on fully-healthy people looking at every health parameter you can imagine: organs, tissues, chemicals, brain function, etcetera.
No harmful effects were caused at any dosage level. Even people who were taking doses that were exponentially higher than any level we recommend, (some of the more exotic animal studies have doses that exceed 800X the recommended dosage) displayed 0 side effects whatsoever. As I am famous for saying, “unless you hit somebody in the eye with the bottle, there is no harm that can be caused by this product”
-AJ Lanigan
Beta Glucan enhances a person’s immune response in a safe way. The average person has about a 30% active immune response. When someone takes our Beta Glucan it raises that person’s immune response to 60%, and in some cases even more, if they are taking the maximum immune response dosage. This allows for your immune system to recognize cells that are both self and non-self more effectively. I’m sure you can imagine the benefits of walking around with a doubled immune response/immune system!
-Better Way Health
Beta Glucan enhances the immune system by improving the immune response when the immune system is confronted by something that does not belong. This could be a foreign body that it sees as “non-self,” something like a virus, a bacteria, a fungus form, or a parasite.
Our Beta-1, 3D Glucan is an intensely purified, highly active form of Beta Glucan; that, when taken orally with a glass of water, attaches to specific sites on the immune cells: the CR3 receptors. By attaching or binding to these specific sites, it activates these cells. It’s like putting the cells on “high alert” to the foreign bodies that they see as non-self. This process is referred to as immune modulation, not stimulation.
Immune stimulation presumably occurs with substances like Echinacea and Colostrum. Beta Glucan modulates or activates but doesn’t over stimulate, which is key to the safety of the compound. Research shows that our Beta-1, 3D Glucan is a highly effective immune modulator. It’s easily absorbed through, what we call, the Peyer’s Patches in the Small Intestine. Once these beta glucan “micro-particles” are taken up through this area in the small intestine, they will then be absorbed through phagocytosis or “gobbled up” by the immune cells in the gut.
They’ll travel around the body and it is the immune cells themselves that will digest and secrete the perfect molecule that binds to the CR 3 receptor and activates the immune system.
-AJ Lanigan
Beta Glucan is not temperature sensitive. If it is exposed to extreme hot or cold temperatures, the efficacy of the product will not be impacted. However, we do recommend keeping a close eye on your tracking information, which is sent to you via email with all orders. This way you know when your order will arrive and when you will be able to retrieve it from your mailbox or front door.
Our Beta Glucan is made in Wisconsin, USA and bottled / encapsulated in Oregon, USA.
Our highly purified Beta Glucan powder is encased in PLANTCAPS™, which is a Plant-based capsule made from pullulan – naturally fermented from tapioca.
After 50 years of research, our Beta Glucan has no known side effects, or interactions with a GRAS (Generally Recognized as Safe) rating by the FDA. It is one of the safest, most effective dietary supplements on the market.
Many women take our Beta Glucan while breastfeeding, to help support their immune system. Babies can also benefit from mom's immune system giving the best response possible.
However, if you have any concerns whatsoever, we recommend consulting with your health care professional before use, as a precautionary measure.
Still have questions?
Our ACES Team is always there to help.
High Quality Beta-1, 3D Glucan Made from Baker's Yeast
Buy Beta Glucan 500mgMore Beta Glucan Info
Helpful Links
References
- https://pubmed.ncbi.nlm.nih.gov/17414422/#:~:text=Administration%20of%20beta%2D1%2C3,significant%20decrease%20in%20MPO%20levels.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017669/#:~:text=%CE%B2%2Dglucan%20induced%20the%20production,metalloproteinase%2D9%20from%20human%20keratinocytes.&text=W%2DS%20(0.5%E2%80%931%20mg%2FmL)%2FAureobasidium%20sp.&text=%CE%B2%2Dglucan%20accelerated%20wound%20healing,to%20release%20more%20TNF%2D%CE%B1.
- http://www.ncbi.nlm.nih.gov/pubmed/17895634
- http://www.webmd.com/vitamins-supplements/ingredientmono-1041-beta%20glucans.aspx?activeingredientid=1041&activeingredientname=beta%20glucans.
- http://www.webmd.com/vitamins-supplements/ingredientmono-1041-beta%20glucans.aspx?activeingredientid=1041&activeingredientname=beta%20glucans
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566984/
- https://pubmed.ncbi.nlm.nih.gov/17895634/
- https://pubmed.ncbi.nlm.nih.gov/18382858/
- https://www.medscape.com/viewarticle/752221
- http://www.webmd.com/vitamins-supplements/ingredientmono-1041-beta%20glucans.aspx?activeingredientid=1041&activeingredientname=beta%20glucans
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